Mrs. Colbert was the villainess from "The Secret," the second season finale of Tales From the Crypt.
She was played by Grace Zabriskie.
Mrs. Colbert and her husband adopted 12-year-old Theodore from an orphanage, and they mainly stuff him full of sweets and keep him in his room, under the watchful eye of their servant, Tobias. Later in the episode, Tobias attempts to escape with Theodore, when he encountered Mrs. Colbert at the stairway.
Mrs. Colbert turned heel and revealed herself as a vampire when she flashed her fangs at Tobias and Theodore. She also revealed that she was to give Tobias immortality in return for watching Theodore, and even threatened to take Theodore should Tobias walk out. Later on, the evil Mrs. Colbert hissed in wicked glee as she watched her vampire husband kill Tobias, and the couple chased after Theodore. However, Theodore revealed that he is a werewolf and devoured the couple.